Innoviant -- A Prescription Solutions Company
Pharmacy Passages: Your Source for Information About Changes to the Innoviant Preferred Products List
 
June 2010

Innoviant's Business Committee meets monthly to evaluate product status (tier placements) and new prescription products approved by the Food and Drug Administration (FDA). The committee makes decisions based on information and recommendations from Prescription Solutions® National Pharmacy & Therapeutics (NP&T) Committee, which is comprised of independent physician providers, affiliated plan physicians and pharmacists.

Change Summary Table

The following table is an at-a-glance summary of decisions made at May committee meetings. Details about products and decisions are further outlined in the "review details" section of this newsletter. All changes are effective August 1, 2010 unless otherwise noted.

  Table Key  

Δ Change

• No Change   + Addition - Deletion
  Tier 3 (Nonpreferred)   Tier 2 (Preferred)   Prior Authorization (PA)
  Δ 8-MOP   + Differin Lotion   + 8-MOP
  Δ Alahist DM       + Accutane
  Δ Aldara   DACON   + Amnesteen
  Δ Aldex DM   + Exalgo (eff. 6-1-10)   + Androderm
  Δ Analpram E Kit       + Androgel
  Δ Brovex PEB DM   *Specialty Pharmacy (SPP)   + Celebrex
  Δ Brovex PSB DM   + Hizentra   + Claravis
  Δ Clariforam EF       + Delatestryl (SPP)
  Δ Depo-Testosterone   Step Edit   + Depo-Testosterone (SPP)
  Δ Emend, Emend Pak   + Valturna   + Emend, Emend Pak
  Δ Evoclin       + Femara
  Δ Lotronex   Gender Edit   + Hizentra (SPP) eff. 7-1-10
  Δ Nitromist   + Lotronex   + Ketek
  Δ Pennsaid       + Lotronex
  Δ Qutenza Kit 8%   Quantity Limit (QL)   + Oxsoralen
  Δ Skelaxin   + Aldara   + Oxsoralen Ultra
  + Tirosint   Δ butorphanol NS   + Regranex
  Δ Triaz Cloths   Δ Emend   + Sotret
  + Zirgan   Δ Emend Pak   + Striant
  + Zyclara   + Evoclin   + Testim
      + Exalgo   + testosterone cypionate inj. (SPP)
      + imiquimod 5% cream  
      + Zirgan   + testosterone enanthate inj. (SPP)
      + Zyclara  
           
     
 

Review Details

The NP&T Committee performs evidence-based clinical reviews of new products, line extensions, therapy classes, formulary placements, generic alternatives and clinical programs. Tier placement and utilization management edits promote safe, cost-effective use of products. Detailed information about the "Change Summary Table" is provided below.

 
Table Key
Plan Design
Open = all generics at tier-1 and all brands at tier-2 (or all medications at tier-1)
Select = generics at tier-1, preferred brands at tier-2 and nonpreferred brands at tier-3
Closed = generics at tier-1 and preferred brands at tier-2
(nonpreferred products are not covered or may require authorization for coverage)
  PPL Status:
G = Generic
PB= Preferred brand
N = Nonpreferred brand
 

Copay Tier:
1 = Generic
2 = Brand/Preferred brand
3 = Nonpreferred brand
0 = Not covered/other

 

Table Header
  New Specialty Medications
Please note: If your plan includes the specialty pharamcy program (SPP), your members may get specialty products from Prescription Solutions® Specialty Pharmacy for your plan's applicable copay. If your plan does not include the SPP, your members may get self-injectable specialty medications from retail pharmacies or specialty products may be covered under the medical plan. Specialty Program medications limited to a 30 day supply.
 

Hizentra, Immune Globulin Subcutaneous (Human), 20% Liquid

Indicated for the treatment of primary immunodeficiency.

  • Specialty Pharmacy Program (SPP) only
  • Prior Authorization
  N   2   3   0
Table Header
  New Medications (non specialty)
 

Differin (adapalene) Lotion, 0.1%

Used for the topical treatment of acne vulgaris in patients 12 years and older.

  • Line extension (new dose form)
  • Added to preferred status (effective 6-1-10)
  • Non-standard item: Topical Retinoid Acne Products
  PB   2   2   2
 

Exalgo (hydromorphone HCl) Extended-Release Tablets

An opioid agonist indicated for once daily administration for the management of moderate to severe pain in opioid tolerant patients requiring continuous, around-the-clock opioid analgesia for an extended period of time.

  • New dose form
  • Quantity Limit (effective 6-1-10)
  • DACON edit (effective 6-1-10)
  N   2   3   0
 

Nitromist (nitroglycerin lingual aerosol 400 mcg spray)

Used for the acute relief of an attack or acute prophylaxis of angina pectoris due to coronary artery disease.

  • New dose form
  N   2   3   0
 

Pennsaid (diclofenac sodium topical solution)

A topically applied nonsteroidal anti-inflammatory drug (NSAID) used for the treatment of the signs and symptoms of osteoarthritis of the knee(s).

  • New dose form
  N   2   3   0
 

Qutenza (capsaicin) 8% patch

Indicated for the management of neuropathic pain associated with postherpetic neuralgia (pain after shingles).

  • New dose form
  N   2   3   0
 

Tirosint (levothyroxine sodium) Capsule

A synthetic levothyroxine product used as replacement or supplemental therapy in congenital or acquired hypothyroidism of any etiology, and for the treatment or prevention of various types of euthyroid goiters.

  • New dose form
  N   2   3   0
 

Triaz (benzoyl peroxide) Foaming Cloths

Used in the topical treatment of acne vulgaris.

  • Moved to nonpreferred status
  N   2   3   0
 

Zirgan (ganciclovir ophthalmic gel) 0.15%

A topical ophthalmic antiviral that is indicated for the treatment of acute herpetic keratitis (dendritic ulcers).

  • New dose form
  • Quantity Limit
  N   2   3   0
 

Zyclara (imiquimod) Cream 3.75%

Topical treatment of clinically typical, visible or palpable actinic keratoses (AK) of the full face or balding scalp in immunocompetent adults.

  • Line extension (new strength)
  • Quantity Limit
  N   2   3   0
Table Header
  Preferred Products List (PPL) Updates
 

Alahist DM (phenylephrine, brompheniramine, dextromethorphan)
Aldex DM (phenylephrine, pyrilamine, dextromethorphan)
Brovex PEB DM (phenylephrine, brompheniramine, dextromethorphan)
Brovex PSB DM (pseudoephedrine, brompheniramine, dextromethorphan)

Combination products used for the temporary relief of cough, cold or allergy symptoms.

  • Moved to nonpreferred status. Generic equivalent available
  N   2   3   0
 

Aldara (imiquimod) Cream 5%

Used for the topical treatment of actinic keratoses (AK) on the face or scalp in immunocompetent adults, for biopsy-confirmed, primary superficial basal cell carcinoma (sBCC) in immunocompetent adults, and for external genital and perianal warts/condyloma acuminata in patients 12 years old or older.

  • Moved to nonpreferred status. Generic equivalent available.
  • Quantity Limit added (also applies to generic equivalent product)
  N   2   3   0
 

Analpram-E Kit (pramoxine 1%/hydrocortisone 2.5% cream with pramoxine 1% wipes kit)

A combination medication used to treat minor pain, itching, swelling, and discomfort caused by hemorrhoids and other problems of the anorectal area.

  • Moved to nonpreferred status. Generic equivalent available.
  N   2   3   0
 

Clarifoam EF(sodium sulfacetamide 10%, sulfur 5% foam)

Used for the topical control of acne vulgaris, acne rosacea and seborrheic dermatitis.

  • Moved to nonpreferred status. Generic equivalent available.
  N   2   3   0
 

Evoclin (clindamycin phosphate) Foam

Indicated for topical application in the treatment of acne vulgaris.

  • Moved to nonpreferred status. Generic equivalent available.
  • Quantity Limit added (also applies to generic equivalent product)
  N   2   3   0
 

Skelaxin (metaxalone)

Used as an adjunct to rest, physical therapy and other measures for the symptomatic relief of acute painful musculoskeletal conditions.

  • Moved to nonpreferred status. Generic equivalent available.
  N   2   3   0
 

Lotronex (alosetron hcl)

A selective serotonin 5-HT3 antagonist indicated only for women with severe diarrhea-predominant irritable bowel syndrome with specific clinical features.

  • Moved to nonpreferred status
  • Added to Prior Authorization program
  • Gender Edit added (coverage allowed for female members only)
  • DACON edit
  N   2   3   0
 

8-MOP (methoxsalen capsules)

A photochemotherapy agent (used in conjunction with UVA radiation) for the treatment of disabling psoriasis, idiopathic vitiligo, and cutaneous T-cell lymphoma (CTCL).

  • Moved to nonpreferred status
  • Added to Prior Authorization program
  • Current utilizers will be grandfathered for continued use without PA or change in tier status.
  N   2   3   0
 

Emend (aprepitant), Emend Pak

Used for the prevention of acute and delayed nausea and vomiting associated with initial and repeat courses of moderately emetogenic and highly emetogenic chemotherapy.

  • Moved to nonpreferred status
  • Added to Prior Authorization program
  • Quantity Limit Revised
  • Current utilizers will be grandfathered for continued use without PA or change in tier status.
  N   2   3   0
Table Header
  Utilization Management Program: DACON (non-Specialty medications)
 

Exalgo

  • Added to DACON program (effective 6-1-10)
  N   2   3   0
Table Header
  Utilization Management Program: Prior Authorization (non-Specialty or Specialty Pharmacy Program option medications)
 

Amnesteen, Claravis, Sotret

  • Added to Prior Authorization program.Current utilizers grandfathered for continued use without PA.
  G   1   1   1
 

Androderm, Androgel, Femara

  • Added to Prior Authorization program.Current utilizers grandfathered for continued use without PA.
  PB   2   2   2
 

8-MOP, Accutane, Celebrex, Emend, Emend Pak, Ketek, Lotronex, Oxsoralen, Oxsoralen Ultra, Regranex, Striant, Testim

  • Added to Prior Authorization program. Current utilizers grandfathered for continued use without PA.
  N   2   3   0
Table Header
  Utilization Management Program: Quantity LImits
 

butorphanol nasal spray

  • Quantity Limit revised from 4 bottles per month to 3 bottles per month.
  G   1   1   1
 

Emend, Emend Pak

  • Quantity Limit for Emend is being revised from 3 capsules per month to the following:
    Emend 40 mg = 1 capsule per prescription
    Emend 80 mg = 2 capsules per prescription
    Emend 125 mg = 1 capsule per prescription
  • Quantity Limit for Emend Pak is being revised from 1 pack per month to 1 pack per prescription
  N   2   3   0
 

Aldara (imiquimod 5% cream), Evoclin, Exalgo, Zirgan, Zyclara

  • Exalgo added to Quantity Limits program (effective 6-1-10)
  • Aldara, Evoclin, Zirgan, Zyclara added to Quantity Limits program (effective 8-1-10)
  • QL also applies to generic equivalent products, noted in parentheses
  N   2   3   0
Table Header
  Utilization Management Program: Step Edit
 

Valturna (aliskiren/valsartan)

  • A combination product used for the treatment of hypertension.
  • Electronic step edit added. Requires step 1 therapy with ACE inhibitor or ACE inhibitor combination, or ARB or ARB combination.
  PB   2   2   2
Table Header
  Specialty Pharmacy Program
SPP medications added to Prior Authorization
 

Delatestryl (testosterone enanthate inj), Depo-Testosterone (testosterone cypionate inj), Hizentra (effective 7/1/10)

  • Prior Authorization added to Hizentra (effective 7-1-10)
  • Prior Authorization added to Delatestryl and Depo-testosterone (effective 8-1-10)
  • Current utilizers grandfathered for continued use without PA
  • PA also applies to generic equivalent products, noted in parentheses
  • Product may be available through the retail benefit depending on benefit design.
  N   2   3   0
  Specialty Pharmacy Program - SPP medications with status change
 

Depo-Testosterone (testosterone cypionate inj)

  • Product moving to nonpreferred status (generic equivalent available)
  • Product may be available through the retail benefit depending on benefit design.
  N   2   3   0

Current information related to Innoviant and its
offerings is available at www.innoviant.com.
A copy
of this newsletter can also be found on the website (http://www.innoviant.com/Common/Publications.aspx?show=cust).

This newsletter does not imply coverage. Plan booklets provide specific benefit and coverage limitations.

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Innoviant - a Prescription Solutions company